VIP 10mg: Vasoactive Intestinal Peptide

Vasoactive Intestinal Peptide (VIP) is a naturally occurring 28-amino-acid neuropeptide widely expressed in the central nervous system, gastrointestinal tract, and immune tissues. In research environments, VIP is studied for its potential roles in neuroprotection, immune modulation, anti-inflammatory pathways, bronchodilation, and smooth-muscle relaxation.

VIP is an important tool in studies exploring neurological, respiratory, gastrointestinal, and immune-cell signaling.

Scientific Background

Discovered in 1970, VIP belongs to the secretin/glucagon peptide family. It functions as a neurotransmitter and hormone, binding primarily to VPAC1 and VPAC2 receptors.

In preclinical and in-vitro research, VIP is associated with:

• cAMP pathway activation

• Smooth-muscle relaxation

• Modulation of inflammatory cytokines

• Regulation of gastric secretions

• Neuroprotective signaling

• Immune-cell communication

Because of its broad biological reach, VIP is a versatile peptide in multiple experimental fields.

Research Areas of Interest

All information below is intended strictly for laboratory, scientific, and in-vitro research purposes only.

1. Neuroprotective & Neurological Research

VIP is evaluated in studies exploring:

• Neuronal survival pathways

• Synaptic plasticity

• Protective signaling against oxidative stress

2. Immune Modulation

Research investigates VIP’s potential influence on:

• T-cell balance (Th1/Th2 modulation)

• Anti-inflammatory cytokine regulation

• Reduction of inflammatory mediators

3. Respiratory / Pulmonary Models

VIP is of interest in:

• Bronchodilation studies

• Airway smooth-muscle relaxation

• Pulmonary vascular regulation

4. Gastrointestinal Function

VIP plays a significant role in:

• Regulation of intestinal motility

• Modulation of gastric secretions

• Gut-brain hormonal signaling

5. Cardiovascular & Vascular Research

Because VIP is a potent vasodilator, preclinical models explore its effects on:

• Blood-flow regulation

• Smooth-muscle relaxation

• Vascular tone

These findings are based on preclinical and in-vitro experiments and are not validated for human therapeutic use.

Molecular Profile

• Peptide: VIP (Vasoactive Intestinal Peptide)

• Sequence: HSDAVFTDNYSRVNQGESSRLRRHF-NH₂ (28 amino acids)

• Family: Secretin/Glucagon Peptide Superfamily

• Form: Lyophilized powder

• Purity: ≥ 98% (HPLC tested)

Storage & Stability

• Store lyophilized peptide at –20°C

• Protect from heat, moisture, and light

• Reconstituted solutions should be used promptly or stored per laboratory protocol

• Avoid repeated freeze-thaw cycles

  Each 3ml vial is formulated with 5mg of highly purified (>99%) lyophilized VIP, produced in sterile environments that meet research-grade standards. Prime Peptides validates every batch through third-party laboratory testing to ensure exact molecular composition, stable peptide structure, and consistent results suitable for a wide range of experimental designs.