GHK-Cu 100mg: Copper Peptide

GHK-Cu is a complex of the tripeptide GHK (glycyl-L-histidyl-L-lysine) and copper, which is found naturally in the human body. This complex has antioxidant, anti-inflammatory, and regenerative properties, and is often used in anti-aging and wound-healing products to stimulate collagen production, improve skin elasticity, and promote tissue repair. GHK-Cu levels in the body decrease with age, which is why it is of particular interest for its potential to counteract age-related effects

Scientific Background

GHK (glycyl-L-histidyl-L-lysine) naturally occurs in human plasma, saliva, and tissues.
When bound to copper (GHK-Cu), it exhibits unique biological activities relevant to:

• Skin regeneration & remodeling

• Anti-inflammatory signaling

• DNA repair pathways

• Collagen and glycosaminoglycan synthesis

• Wound-healing and tissue-repair processes

• Stem-cell activation and protection

In research models, GHK-Cu has demonstrated the ability to:

• Support fibroblast activity

• Increase expression of repair-related genes

• Improve cellular resilience under stress

• Modulate cytokine activity in damaged tissue

• Influence gene expression associated with aging and tissue breakdown

GHK-Cu is often investigated as a biomimetic signal peptide for skin and tissue repair.

Research Areas of Interest

All information below is intended strictly for scientific, laboratory, and in-vitro research only.

1. Skin Regeneration & Repair Models

Researchers study GHK-Cu for potential effects on:

• Fibroblast proliferation

• Collagen I & III synthesis

• Dermal remodeling pathways

• Wound-closure studies

2. Anti-Inflammatory & Antioxidant Pathways

GHK-Cu is used to explore:

• Reduction of inflammatory cytokines

• Decreased oxidative stress markers

• Modulation of NF-κB–related pathways

3. Hair-Follicle & Skin-Cell Research

Experiments evaluate:

• Dermal papilla cell activity

• Hair-follicle signaling molecules

• ECM (extracellular matrix) remodeling

4. DNA Repair & Gene-Expression Studies

Researchers examine GHK-Cu’s involvement in:

• DNA repair enzyme pathways

• Gene expression linked to cellular aging

• Tissue-protective gene profiles

5. Cosmetic & Anti-Aging Research Models

Because of its skin-focused activity, GHK-Cu is widely used to study:

• Firmness and elasticity pathways

• Fine-line and wrinkle–related signaling

• Age-related degradation of ECM proteins

All findings are preclinical or in-vitro only, not validated clinical outcomes.

Molecular Profile

• Peptide: GHK-Cu (Copper Tripeptide-1)

• Type: Copper-binding tripeptide

• Sequence: Gly-His-Lys

• Length: 3 amino acids

• Molecular Weight: ~340.4 g/mol

• Form: Lyophilized powder

• Purity: ≥ 98% (HPLC tested)

Storage & Stability

• Store lyophilized peptide at –20°C

• Keep away from moisture, heat, and light

• Use reconstituted solution promptly or store as per lab protocol

• Avoid repeated freeze–thaw cycles

Each 3ml vial is formulated with 100mg of highly purified (>99%) lyophilized GHK-Cu, produced in sterile environments that meet research-grade standards. Prime Peptides validates every batch through third-party laboratory testing to ensure exact molecular composition, stable peptide structure, and consistent results suitable for a wide range of experimental designs.