5-Amino-1MQ 5mg: NNMT Inhibitor

Scientific Background

NNMT is an enzyme found in liver, fat tissue, and other metabolic organs. It regulates:

• NAD⁺ availability

• Cellular energy balance

• Methylation & SAM/SAH pathways

• Adipocyte metabolic rate

Overexpression of NNMT has been associated with:

• Reduced energy expenditure

• Fat accumulation

• Impaired metabolic signaling

5-Amino-1MQ is investigated for its ability to inhibit NNMT, helping researchers study:

• Increased cellular NAD⁺ levels

• Enhanced metabolic rate

• Reduced fat-cell hypertrophy

• Improved mitochondrial signaling

Research Areas of Interest

All information below is strictly for laboratory, scientific, and in-vitro research only.

1. NAD⁺ & Mitochondrial Metabolism

5-Amino-1MQ is used to study:

• NAD⁺ boosting pathways

• Mitochondrial activation

• Energy-production efficiency

2. Adipocyte (Fat-Cell) Biology

Researchers use 5-Amino-1MQ to investigate:

• Decreased fat-cell size (hypertrophy)

• Increased fat-cell energy expenditure

• Lipid metabolism

• Inhibition of NNMT in adipose tissue

3. Metabolic & Energy-Balance Studies

Research explores potential roles in:

• Caloric-expenditure pathways

• Metabolic flexibility

• Cellular fuel utilization

4. Methylation Pathways & NNMT Signaling

NNMT regulates SAM (S-adenosyl methionine) and methylation status.
5-Amino-1MQ allows investigations into:

• Epigenetic metabolic control

• Methyl-donor utilization

• NNMT-related gene expression

5. Obesity & Fat-Metabolism Models

In preclinical settings, NNMT inhibition is studied for:

• Reduced fat mass

• Improved metabolic markers

• Enhanced energy turnover

All findings are based on preclinical and in-vitro research—no clinical claims.

Molecular Profile

• Compound: 5-Amino-1-methylquinolinium (5-Amino-1MQ)

• Type: Small-Molecule NNMT Inhibitor

• Formula: C₁₀H₁₁N₂⁺

• Molecular Weight: ~ 159.21 g/mol

• Form: Lyophilized powder

• Purity: ≥ 98% (HPLC tested)

Storage & Stability

• Store at –20°C in a cool, dry environment

• Protect from heat, moisture, and light

• Reconstituted solutions should be used promptly or stored per laboratory protocol

• Avoid repeated freeze-thaw cycles

  Each 3ml vial is formulated with 50mg of highly purified (>99%) lyophilized 5-Amino-1MQ, produced in sterile environments that meet research-grade standards. Prime Peptides validates every batch through third-party laboratory testing to ensure exact molecular composition, stable peptide structure, and consistent results suitable for a wide range of experimental designs.