IGF-1 LR3 1mg: Long R3 Insulin-Like Growth Factor-1

 IGF-1 LR3 (Insulin-like Growth Factor-1 Long R3) is a lab-engineered version of IGF-1 with a longer-lasting effect, making it useful for research on muscle growth, tissue repair, and metabolism. Scientists study this peptide because it binds to IGF-1 receptors, helping to increase protein production, promote muscle development, and support cell regeneration. These properties make IGF-1 LR3 an important subject in studies on muscle recovery, injury repair, and overall tissue health. Researchers are also exploring its role in metabolism and how it may influence insulin sensitivity and fat utilization.

Scientific Background

Native IGF-1 is a 70-amino-acid growth factor involved in:

• Muscle cell proliferation

• Tissue growth & repair

• Insulin-related signaling cascades

• Developmental biology

• Cellular metabolism

IGF-1 LR3 includes two main modifications that enhance research utility:

1. An Arginine substitution at position 3 (“R3”), reducing IGF-binding protein interference

2. A 13-amino-acid N-terminal extension, increasing half-life and activity

These changes allow IGF-1 LR3 to remain active longer and interact more efficiently with IGF-1 receptors in vitro.

Mechanism of Action

• Binds IGF-1 receptor (IGF1R) → activates PI3K/AKT/mTOR pathway
• Promotes protein synthesis, cell proliferation, satellite cell activation
• Inhibits apoptosis and enhances nutrient partitioning
• Bypasses IGFBPs → free IGF-1 activity ↑ 100–1000x vs. native IGF-1

The Details:

• Quantity: 1mg per vial
• Purity: ≥99%, (HPLC Testing)
• Packaging: Tamper-proof, securely sealed vials
• Source: Synthesized using advanced peptide synthesis techniques
• Note: This product is sold in lyophilized powder form and must be reconstituted before use.

Research Applications

• Muscle Growth and Regeneration Studies: IGF-1 LR3 is widely researched for its role in stimulating muscle hypertrophy and recovery.
• Cellular Repair and Regenerative Medicine: Studies focus on IGF-1 LR3’s ability to promote tissue healing and support cellular growth.
• Metabolic Research: Researchers explore how this peptide influences glucose uptake, insulin sensitivity, and fat metabolism.
• Neurological and Cognitive Function: Investigations are ongoing into IGF-1 LR3’s role in neuroprotection and brain cell regeneration.

Why IGF-1 LR3?

• Gold standard for localized hypertrophy
• Ideal for plateau-breaking or injury recovery
• No aromatization or androgenic sides

Each 3ml vial is formulated with 1mg of highly purified (>99%) lyophilized IGF-1 LR3, produced in sterile environments that meet research-grade standards. Prime Peptides validates every batch through third-party laboratory testing to ensure exact molecular composition, stable peptide structure, and consistent results suitable for a wide range of experimental designs.