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Tesamorelin 20mg: GNRH Analogue

Original price was: $175.00.Current price is: $150.00.

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Tesamorelin (also known as Egrifta™, TH9507) is a synthetic growth hormone-releasing hormone (GHRH) analog consisting of 44 amino acids. It is a modified version of natural GHRH with a trans-3-hexenoic acid substitution at the N-terminus, which enhances stability and half-life. FDA-approved in 2010, it is the only GHRH analog indicated for reducing excess abdominal fat in HIV-associated lipodystrophy.

Tesamorelin is a synthetic analogue of growth hormone-releasing hormone (GHRH). It works by stimulating the pituitary gland to produce and release the body’s own growth hormone, which in turn increases levels of insulin-like growth factor-1 (IGF-1). While it increases growth hormone and IGF-1 levels, its primary approved use is to reduce excess visceral fat (lipodystrophy) in adults with HIV.
Scientific Background

Tesamorelin is based on the endogenous GHRH sequence with a trans-3-hexenoic acid modification at the N-terminus.
This structural adjustment improves:

  • Peptide stability

  • Receptor binding affinity

  • Protection from enzymatic degradation

  • GH secretory potential

In preclinical research, Tesamorelin has been shown to influence:

  • Pulsatile GH release

  • Circulating IGF-1 levels

  • Lipid-metabolism regulation

  • Fat-oxidation pathways

  • Endocrine feedback loops

Because of its robust GH-axis activity, Tesamorelin is one of the most potent GHRH analogues used in scientific studies.


Research Areas of Interest

All information below is intended strictly for scientific, laboratory, and in-vitro research only.

1. Growth Hormone Secretion & Endocrine Signaling

Tesamorelin is widely studied for:

  • GH pulse amplitude and frequency

  • Receptor-mediated activation of pituitary somatotrophs

  • GH/IGF-1 axis dynamics

2. Lipid Metabolism & Fat-Reduction Pathways

Researchers evaluate Tesamorelin’s influence on:

  • Visceral-fat metabolism

  • Lipolytic signaling

  • Triglyceride-related pathways

3. IGF-1 Modulation & Cellular Growth Studies

Tesamorelin is used to explore:

  • IGF-1 expression changes

  • Nutrient-partitioning models

  • Protein-synthesis signaling

4. Pituitary & Hypothalamic Interaction Models

Research includes:

  • Receptor-driven GH release

  • Neuroendocrine-axis regulation

  • Comparative studies with CJC-1295 and GRF analogues

5. Comparative GHRH Research

Tesamorelin is frequently compared to:

  • CJC-1295 DAC

  • CJC-1295 no DAC (Mod GRF 1-29)

  • Sermorelin

  • Hexarelin and Ipamorelin (GHRPs)

All findings come from preclinical or in-vitro experimental models.


Molecular Profile
  • Peptide: Tesamorelin

  • Type: Synthetic GHRH analogue

  • Sequence Length: 44 amino acids

  • Modification: Trans-3-hexenoic acid at position 1

  • Molecular Weight: ~5,120 Da

  • Form: Lyophilized powder

  • Purity: ≥ 98% (HPLC tested)


Storage & Stability
  • Store lyophilized peptide at –20°C

  • Protect from heat, moisture, and light

  • Use reconstituted peptide promptly or store per lab guidelines

  • Avoid repeated freeze–thaw cycles


Each 3ml vial is formulated with 20mg of highly purified (>99%) lyophilized Tesamorelin, produced in sterile environments that meet research-grade standards. Prime Peptides validates every batch through third-party laboratory testing to ensure exact molecular composition, stable peptide structure, and consistent results suitable for a wide range of experimental designs.

 

 

What Are Peptides?

Peptides are short chains of amino acids studied in laboratory and research settings for their interaction with biological pathways.

Usage & Storage

Store peptides in a cool, dry place away from direct light. For long-term stability, keep lyophilized (powder) peptides refrigerated at 2–8°C. Once reconstituted, store in the refrigerator and use within a short period to maintain integrity. Avoid repeated temperature changes.

Shipping & Delivery

All orders ship within 24 hours (Monday–Friday) from our facility. Delivery typically takes 1-2 business days depending on your location. Once shipped, you’ll receive a tracking number to monitor your order in real time.

Payment Information

We currently accept E-transfer only. Payment instructions are sent automatically after checkout.

Disclaimer: All peptides offered by Prime Peptides are strictly intended for laboratory research purposes only. These products are not approved for human consumption, medical use, therapeutic applications, or diagnostic procedures.
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