Epitalon 50mg: Anti-aging Research Peptide

Epitalon (also known as Epithalon or Epithalamin) is a synthetic tetrapeptide consisting of the amino-acid sequence Ala-Glu-Asp-Gly (AEDG). It is widely studied for its potential roles in telomere biology, cellular aging, oxidative stress, pineal gland function, and circadian-regulation pathways in controlled laboratory environments.

Originally derived from the natural peptide epithalamin found in the pineal gland, Epitalon is one of the most researched peptides in the field of experimental aging science.

Scientific Background

Epitalon’s research interest centers around its reported effects on:

• Telomerase activation in cellular models

• DNA and chromatin structure support

• Melatonin regulation via pineal-gland pathways

• Antioxidant and anti-stress signaling

• Cellular lifespan extension in vitro

Because telomere shortening and oxidative stress are major themes in aging biology, Epitalon is frequently used in studies related to longevity and cellular senescence.

Research Areas of Interest

All information below is intended strictly for laboratory, scientific, and in-vitro research.

1. Telomere & Telomerase Research

In cellular studies, Epitalon has been associated with:

• Increased telomerase activity

• Support for telomere length maintenance

• Reduced cellular senescence markers

2. Pineal Gland & Circadian Rhythm Models

Research evaluates Epitalon’s potential effects on:

• Melatonin synthesis pathways

• Light/dark cycle regulation

• Pineal-gland peptide signaling

3. Oxidative Stress & Longevity Studies

Epitalon is used in models exploring:

• Reduction of reactive oxygen species

• Improved cellular resilience

• Stress-response signaling

4. Cell-Cycle & DNA-Repair Pathways

Scientists use Epitalon to investigate:

• Chromosomal stability

• Gene-expression patterns associated with aging

• Protective peptide signaling in stressed cells

5. Immunological & Endocrine Interactions

Exploratory research includes:

• Immune modulation

• Neuroendocrine signaling

• Cross-talk between circadian and hormonal systems

These findings come from preclinical and in-vitro models — not from validated clinical outcomes.

Molecular Profile

• Peptide: Epitalon (Epithalon / Epithalamin)

• Sequence: AEDG (Ala-Glu-Asp-Gly)

• Length: 4 amino acids (tetrapeptide)

• Molecular Weight: ~ 389 Da

• Category: Pineal-derived peptide analogue

• Form: Lyophilized powder

• Purity: ≥ 98% (HPLC tested)

Why Epitalon?

• Pioneer in peptide gerontology—backed by 30+ years of Russian research.
• Ideal for longevity enthusiasts, shift workers, or aging optimization.
• Emerging evidence for epigenetic clock reversal (Horvath clock ↓ in pilots).

Storage & Stability

• Store lyophilized peptide at –20°C

• Protect from heat, light, and moisture

• Reconstituted solutions should be used promptly or stored according to laboratory protocol

• Avoid repeated freeze-thaw cycles

  Each 3ml vial is formulated with 50mg of highly purified (>99%) lyophilized Epitalon, produced in sterile environments that meet research-grade standards. Prime Peptides validates every batch through third-party laboratory testing to ensure exact molecular composition, stable peptide structure, and consistent results suitable for a wide range of experimental designs.